Sugi Predict

Sugi Predict / Compounds / SCHEMBL1779503

SCHEMBL1779503

SCHEMBL1779503

Cn1nc(CO)cc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 2/20 0.52
▸ CA1 P00915 5/20 0.49
▸ CA2 P00918 5/20 0.49
▸ CA9 Q16790 5/20 0.49
▸ NR1H4 Q96RI1 1/20 0.47
▸ MPO P05164 1/20 0.43
▸ NOTUM Q6P988 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ CNR1 P21554 1/20 0.41
▸ CNR2 P34972 1/20 0.41
▸ GRM5 P41594 1/20 0.41
▸ DDB1 Q16531 1/20 0.40
▸ CRBN Q96SW2 1/20 0.40
▸ SLC16A3 O15427 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ P2RX7 Q99572 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25731620 0.86 CA1 (0.51) PTGS2CA1CA2CA9NR1H4
SCHEMBL10275017 0.84 CNR1 (0.45) PTGS2NR1H4MPOCNR1CNR2
SCHEMBL22769348 0.83 NR1H4 (0.45) PTGS2CA1CA2CA9NR1H4
SCHEMBL5026993 0.83 PTGS2 (0.51) PTGS2CA1CA2CA9NR1H4
SCHEMBL21807369 0.83 CSNK1D (0.46) PTGS2CA1CA2CA9NR1H4
SCHEMBL6163522 0.82 KCNH2 (0.40) PTGS2CA1CA2CA9NR1H4
SCHEMBL3758693 0.82 MPO (0.46) PTGS2CA1CA2CA9NR1H4
SCHEMBL19585848 0.82 NR1H4 (0.43) PTGS2NR1H4MPOCNR1CNR2
SCHEMBL20805341 0.81 NR1H4 (0.44) PTGS2CA1CA2CA9NR1H4
SCHEMBL22912537 0.79 POLB (0.43) PTGS2NR1H4MPOCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 — — EP claimed
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2026-04-21 — — US disclosed
US-20240398959-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2024-12-05 — — US disclosed
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2024-05-28 — — US disclosed
WO-2023107552-A2 PURINES AND METHODS OF THEIR USE Kineta, Inc. (US) 2023-06-15 — — WO disclosed
US-20220313826-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2022-10-06 — — US disclosed
US-10849982-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2020-12-01 — — US disclosed
US-10849982-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2020-12-01 — — US disclosed
CN-109641874-A C for target protein degradation3The glutarimide degron body of carbon connection C4医药公司 2019-04-16 — — CN disclosed
EP-3455218-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 — — EP disclosed
CN-1066716-C Method for separating methanol ESTEVE LABOR DR (ES) 2001-06-06 — — CN disclosed
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 — — EP disclosed
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 — — EP disclosed
US-5849931-A Process for separating carbinols LABORATORIOS DEL DR. ESTEVE S.A. (ES) 1998-12-15 — — US disclosed
US-5849931-A Process for separating carbinols LABORATORIOS DEL DR. ESTEVE S.A. (ES) 1998-12-15 — — US disclosed
CN-1177958-A Method for separating carbinols ESTEVE LABOR DR (ES) 1998-04-01 — — CN disclosed
EP-0808308-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-11-26 — — EP disclosed
EP-0808308-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-11-26 — — EP disclosed
WO-1997020817-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-06-12 — — WO disclosed
WO-1997020817-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-06-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation NEDD4, UBE3A, UBE3C PTGS2 4487/4885CA1 1397/4885CA2 2466/4885
US-10849982-B2 C3-carbon linked glutarimide degronimers for target protein degradation STUB1, UBE3C, UBE3A PTGS2 4320/4885CA1 1568/4885CA2 3567/4885
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation STUB1, UBE3C, UBE3A PTGS2 4320/4885CA1 1568/4885CA2 3567/4885
US-20240398959-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A PTGS2 4320/4885CA1 1568/4885CA2 3567/4885
US-20220313826-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A PTGS2 4320/4885CA1 1568/4885CA2 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.