Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | CDC25C | P30307 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153147 | 0.94 | KCNH2 (0.68) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL11139253 | 0.92 | KCNH2 (0.67) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL3156616 | 0.90 | KCNH2 (0.62) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL3152144 | 0.87 | KCNH2 (0.68) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL5213120 | 0.84 | KCNH2 (0.67) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL3143117 | 0.83 | KCNH2 (0.64) | KCNH2PYCR1SIGMAR1TMEM97CRHBP | |
| SCHEMBL3146890 | 0.83 | KCNH2 (0.62) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL5208558 | 0.83 | KCNH2 (0.71) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL3154646 | 0.83 | PYCR1 (0.66) | KCNH2MAPTPYCR1SIGMAR1TMEM97 | |
| SCHEMBL7132148 | 0.82 | MAPT (0.53) | KCNH2MAPTPYCR1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152654-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152654-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | KCNH2 3850/4885MAPT 4213/4885PYCR1 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.