Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479587 | 0.99 | MIF (0.63) | MIFBCHENOTUMP2RX7CA12 | |
| SCHEMBL13527011 | 0.85 | NOTUM (0.51) | MIFNOTUMP2RX7CYP1A2CYP2C9 | |
| SCHEMBL21157760 | 0.85 | NOTUM (0.51) | MIFNOTUMP2RX7ROCK2RXRA | |
| SCHEMBL17795429 | 0.84 | P2RX7 (0.61) | MIFBCHEP2RX7CA12CA1 | |
| SCHEMBL13527252 | 0.84 | MIF (0.60) | MIFBCHENOTUMP2RX7CA12 | |
| SCHEMBL13527307 | 0.84 | MIF (0.64) | MIFBCHENOTUMP2RX7CA12 | |
| SCHEMBL17795660 | 0.83 | MIF (0.59) | MIFBCHENOTUMP2RX7CA12 | |
| SCHEMBL13527214 | 0.83 | MIF (0.67) | MIFBCHENOTUMP2RX7CA12 | |
| SCHEMBL16479571 | 0.83 | MIF (0.60) | MIFBCHEP2RX7CA12CA1 | |
| SCHEMBL15060892 | 0.82 | MIF (0.62) | MIFBCHENOTUMP2RX7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152654-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152654-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | MIF 196/4885BCHE 2005/4885NOTUM 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.