Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162036 | 0.78 | NAMPT (0.50) | NPC1RAB9AHPGDSTGFBR1NAMPT | |
| SCHEMBL13162009 | 0.78 | NAMPT (0.50) | NPC1RAB9AHPGDSTGFBR1NAMPT | |
| SCHEMBL17796380 | 0.76 | EGLN1 (0.49) | CHRM4NPC1RAB9AHPGDSPLAT | |
| SCHEMBL17796768 | 0.76 | EGLN1 (0.49) | CHRM4NPC1RAB9AHPGDSPLAT | |
| SCHEMBL29062256 | 0.72 | TAS1R3 (0.54) | CHRM4NPC1RAB9AHPGDSP2RX7 | |
| SCHEMBL13634628 | 0.71 | NPC1 (0.64) | NPC1RAB9ANAMPT | |
| SCHEMBL13162643 | 0.71 | NPC1 (0.64) | NPC1RAB9ANAMPT | |
| SCHEMBL27962651 | 0.71 | NAMPT (0.50) | HPGDSNAMPTDGAT2CYP2C9CYP2C19 | |
| SCHEMBL19877022 | 0.71 | NAMPT (0.50) | HPGDSNAMPTDGAT2CYP2C9CYP2C19 | |
| SCHEMBL7456523 | 0.70 | NAMPT (0.50) | CHRM4HPGDSPLATTGFBR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029031-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-08 | — | — | EP | disclosed |