Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797016 | 0.89 | KIF11 (0.51) | KIF11PTGDR2BACE1SCN9A | |
| SCHEMBL17796943 | 0.88 | PTGDR2 (0.49) | KIF11PTGDR2BACE1SCN9AUSP2 | |
| SCHEMBL17797023 | 0.83 | ERN1 (0.40) | — | |
| SCHEMBL17797007 | 0.79 | PTGDR2 (0.48) | KIF11PTGDR2BACE1SCN9AHPGD | |
| SCHEMBL29188533 | 0.79 | KIF11 (0.51) | KIF11PTGDR2KDM4EUSP2ALDH1A1 | |
| SCHEMBL17796956 | 0.77 | PTGER1 (0.43) | — | |
| SCHEMBL20573163 | 0.77 | CTSA (0.44) | BACE1ALDH1A1HPGD | |
| SCHEMBL28471479 | 0.75 | ALDH1A1 (0.53) | KIF11PTGDR2KDM4EUSP2ALDH1A1 | |
| SCHEMBL3712182 | 0.74 | MRGPRX4 (0.53) | KIF11MRGPRX4 | |
| SCHEMBL28469639 | 0.72 | KIF11 (0.51) | KIF11BACE1KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | Dong-A ST Co., Ltd. (KR) | 2016-06-08 | — | — | EP | disclosed |