Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797013 | 0.89 | KIF11 (0.48) | KIF11PTGDR2BACE1SCN9A | |
| SCHEMBL17796943 | 0.85 | PTGDR2 (0.49) | KIF11PTGDR2BACE1SCN9AKCNN4 | |
| SCHEMBL20573268 | 0.85 | BCL9 (0.40) | SCN9A | |
| SCHEMBL17797007 | 0.79 | PTGDR2 (0.48) | KIF11PTGDR2BACE1SCN9A | |
| SCHEMBL29188533 | 0.79 | KIF11 (0.51) | KIF11PTGDR2KCNN4 | |
| SCHEMBL1753597 | 0.78 | PTGDR2 (0.80) | PTGDR2 | |
| SCHEMBL4971993 | 0.77 | TUBB4A (0.36) | KIF11BACE1SCN9A | |
| SCHEMBL20573270 | 0.77 | SLC6A4 (0.50) | KCNN4 | |
| SCHEMBL20573247 | 0.77 | SCN9A (0.47) | PTGDR2SCN9A | |
| SCHEMBL17796980 | 0.76 | PTGDR2 (0.43) | PTGDR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | Dong-A ST Co., Ltd. (KR) | 2016-06-08 | — | — | EP | disclosed |