Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836796 | 0.85 | KDM4E (0.36) | RORCRIPK1ALDH1A1PGK1ABL1 | |
| SCHEMBL17797202 | 0.85 | RORC (0.35) | RORCRIPK1SLC6A3ADORA3MEN1 | |
| SCHEMBL17797211 | 0.84 | RIPK1 (0.34) | RORCRIPK1ALDH1A1PGK1ABL1 | |
| SCHEMBL2465186 | 0.84 | MAP4K1 (0.32) | ALDH1A1 | |
| SCHEMBL17797217 | 0.84 | KDM4E (0.39) | RIPK1ALDH1A1ABL1KDM4EHSD17B10 | |
| SCHEMBL17797253 | 0.84 | CYP1A2 (0.38) | RORCRIPK1ALDH1A1ABL1KDM4E | |
| SCHEMBL17797215 | 0.84 | RIPK1 (0.37) | RORCRIPK1ALDH1A1ABL1KDM4E | |
| SCHEMBL17797248 | 0.83 | RIPK1 (0.34) | RORCRIPK1ALDH1A1ABL1NUDT1 | |
| SCHEMBL17797262 | 0.82 | MAPK14 (0.34) | RORCRIPK1ALDH1A1ABL1KDM4E | |
| SCHEMBL17797212 | 0.82 | RIPK1 (0.41) | RORCRIPK1ALDH1A1ABL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |