Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797217 | 0.88 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3836957 | 0.87 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19RORCKDM4E | |
| SCHEMBL17797209 | 0.85 | MAPK9 (0.37) | KDM4EKMT2AMAPTHSD17B10TDP1 | |
| SCHEMBL17797202 | 0.85 | RORC (0.35) | RORCMEN1KMT2AMAPTADORA3 | |
| SCHEMBL17797223 | 0.84 | RORC (0.40) | CYP1A2CYP2C9CYP2C19RORCKDM4E | |
| SCHEMBL17797206 | 0.84 | RORC (0.35) | RORCKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17797248 | 0.83 | RIPK1 (0.34) | RORCALDH1A1ADORA3BRD4RIPK1 | |
| SCHEMBL17797234 | 0.83 | RORC (0.37) | CYP1A2CYP2C9CYP2C19RORCKDM4E | |
| SCHEMBL2468173 | 0.82 | ADORA2A (0.39) | KDM4EALDH1A1ADORA3HSD17B10RIPK1 | |
| SCHEMBL17797220 | 0.82 | PDCD1LG2 (0.39) | ADORA3RIPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |