Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CD40 | P25942 | 2/20 | 0.38 |
| ▸ | CD40LG | P29965 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402281 | 0.94 | ENPP2 (0.42) | ENPP2THRBRXFP1MAPTEGFR | |
| SCHEMBL16402301 | 0.87 | ENPP2 (0.52) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL16397550 | 0.85 | ENPP2 (0.49) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL17800246 | 0.82 | THRB (0.48) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL17800247 | 0.81 | ENPP2 (0.46) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL17816533 | 0.81 | ENPP2 (0.46) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL16402264 | 0.79 | ENPP2 (0.44) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL16402228 | 0.78 | ENPP2 (0.46) | ENPP2THRBRXFP1MAPTNT5E | |
| SCHEMBL11765604 | 0.77 | KMT2A (0.65) | ENPP2MAPTKMT2AMEN1NPC1 | |
| SCHEMBL17800245 | 0.76 | THRB (0.43) | ENPP2THRBRXFP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159778-A1 | NOVEL UREIDO DERIVATIVES OF NAPHTHALENESULFONIC ACIDS | NEED PHARMACEUTICALS S.R.L. (IT) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159778-A1 | NOVEL UREIDO DERIVATIVES OF NAPHTHALENESULFONIC ACIDS | UMPS, UTS2R, UROD | ENPP2 991/4885THRB 4576/4885RXFP1 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.