Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.72 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760376 | 1.00 | NAPRT (0.72) | NAPRTDGAT1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL2928501 | 0.98 | NAPRT (0.69) | NAPRTDGAT1RAB9ASMN1; SMN2GAA | |
| SCHEMBL7440808 | 0.86 | NAPRT (0.72) | NAPRTDGAT1RAB9ASMN1; SMN2GAA | |
| SCHEMBL13360579 | 0.84 | NAPRT (0.69) | NAPRTDGAT1RAB9ASMN1; SMN2GAA | |
| 6-Chloronicotinic Acid SCHEMBL29524158 | 0.84 | NAPRT (1.00) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL3748187 | 0.84 | NAPRT (0.69) | NAPRTDGAT1RAB9ASMN1; SMN2GAA | |
| 6-Chloronicotinic Acid SCHEMBL104580 | 0.84 | NAPRT (1.00) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL388168 | 0.82 | NAPRT (0.67) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| 6-Chloronicotinic Acid SCHEMBL523893 | 0.82 | NAPRT (0.96) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| 6-Chloronicotinic Acid SCHEMBL10575126 | 0.82 | NAPRT (0.96) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2052 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192728-A | High-strength composite material for manufacturing plastic shell and preparation method thereof | 深圳市维高模塑有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118307997-B | Durable mildew-proof coating for door plate and preparation method thereof | 广东大自然家居科技研究有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118307997-A | Durable mildew-proof coating for door plate and preparation method thereof | 广东大自然家居科技研究有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-116983267-B | Embedding system of dihydrocannabidiol dinitrate and preparation method and application thereof | 中国农业科学院农产品加工研究所 | 2023-12-19 | — | — | CN | claimed |
| CN-116983267-A | Embedding system of dihydrocannabidiol dinitrate and preparation method and application thereof | 中国农业科学院农产品加工研究所 | 2023-11-03 | — | — | CN | claimed |
| CN-112358487-B | Lappaconitine derivative, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-08-25 | — | — | CN | claimed |
| CN-115536582-A | Preparation method of medical intermediate 6-chloronicotinonitrile | 浙江工业大学 | 2022-12-30 | — | — | CN | claimed |
| WO-2022099937-A1 | LAPPACONITINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院新疆理化技术研究所 | 2022-05-19 | — | — | WO | claimed |
| CN-113717240-A | Nucleoside compound and preparation method thereof | 哈尔滨商业大学 | 2021-11-30 | — | — | CN | claimed |
| CN-109369758-B | Synthesis method and application of 5'- (6-chloronicotinyl ester) -3' -deoxyadenosine | 哈尔滨商业大学 | 2021-04-13 | — | — | CN | claimed |
| CN-108299418-A | A kind of synthetic method of the thiazolyl nicotinamide compound of antiallergy and asthma | 刘双伟 | 2018-07-20 | — | — | CN | claimed |
| CN-103288803-B | Benzimidazole amides compound and its preparation method and application | 郎恒元 | 2017-10-31 | — | — | CN | claimed |
| EP-2032536-B1 | SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-06 | — | — | EP | claimed |
| CN-101495456-B | Substituted pyridyl amide compounds as modulators of the histamine H3 receptor | JANSSEN PHARMACEUTICA NV | 2014-03-19 | — | — | CN | claimed |
| US-7777031-B2 | Substituted pyridyl amide compounds as modulators of the histamine H3 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2010-08-17 | — | — | US | claimed |
| CN-101495456-A | Substituted pyridyl amide compounds as modulators of the histamine H3 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | CN | claimed |
| CN-100488962-C | Derivative of thiadiazoles containing cyclo oxdiazole, synthetic method, and biological activity | UNIV NANKAI (CN) | 2009-05-20 | — | — | CN | claimed |
| EP-2032536-A2 | SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-11 | — | — | EP | claimed |
| WO-2007143422-A2 | SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-13 | — | — | WO | claimed |
| US-20070281923-A1 | SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-06 | — | — | US | claimed |