Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801443 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL17801436 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL17801404 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL17801565 | 0.79 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL17801563 | 0.79 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL17801442 | 0.78 | ATP4A (0.36) | P2RX3L3MBTL1KCNH2 | |
| SCHEMBL17801440 | 0.78 | ATP4A (0.36) | P2RX3L3MBTL1KCNH2 | |
| SCHEMBL2685505 | 0.77 | SMN1; SMN2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL15649015 | 0.77 | SMN1; SMN2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL2685504 | 0.77 | SMN1; SMN2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |