Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | PRNP | P04156 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942847 | 0.81 | MAPT (0.44) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL7547167 | 0.81 | BACE1 (0.46) | BACE1ALDH1A1MEN1KMT2AAR | |
| SCHEMBL28153007 | 0.78 | KMT2A (0.60) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL31716582 | 0.78 | BACE1 (0.43) | BACE1ALDH1A1MEN1KMT2AAR | |
| SCHEMBL2717498 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AARKDM4E | |
| Hydrochloric Acid SCHEMBL28213132 | 0.76 | KMT2A (0.58) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL5264894 | 0.76 | PRNP (0.62) | ALDH1A1MEN1KMT2AKDM4EPRNP | |
| SCHEMBL7983249 | 0.75 | BACE1 (0.56) | BACE1ALDH1A1ARKDM4ELMNA | |
| SCHEMBL17942612 | 0.75 | MCHR1 (0.57) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL17801432 | 0.73 | ALDH1A1 (0.47) | BACE1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| EP-3247692-B1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LTD (IN) | 2022-09-07 | — | — | EP | disclosed |
| US-10336723-B2 | Inhibitors of TrkA kinase | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2019-07-02 | — | — | US | disclosed |
| US-20180009781-A1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2018-01-11 | — | — | US | disclosed |
| EP-3247692-A1 | INHIBITORS OF TRKA KINASE | GVK Biosciences Private Limited (IN) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016116900-A1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009781-A1 | INHIBITORS OF TRKA KINASE | NGFR, NGF, NTRK1 | BACE1 508/4885ALDH1A1 2186/4885MEN1 2623/4885 |
| US-10336723-B2 | Inhibitors of TrkA kinase | NGFR, EDNRA, NGF | BACE1 381/4885ALDH1A1 2317/4885MEN1 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.