Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30274855 | 0.75 | ALOX5 (0.54) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17801529 | 0.74 | ALOX5 (0.44) | ALOX5NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7976747 | 0.67 | ALOX5 (0.53) | ALOX5MEN1KMT2AALDH1A1PKM | |
| SCHEMBL17801568 | 0.67 | ALOX5 (0.56) | ALOX5KMT2AALDH1A1PKMMAPT | |
| SCHEMBL2294520 | 0.65 | MEN1 (0.34) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10025528 | 0.65 | CHRM2 (0.50) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4138469 | 0.64 | MAPT (0.56) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16492187 | 0.64 | — | — | |
| SCHEMBL16358205 | 0.64 | ALOX5 (0.53) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12310995 | 0.63 | CHRM2 (0.48) | ALOX5NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | NATIONAL SCIENCE FOUNDATION | 2020-04-09 | — | — | US | disclosed |
| WO-2016090060-A1 | NUCLEOPHILE-TRIGGERED DEGRADBLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | MRE11, ENDOD1, DNASE1 | ALOX5 1214/4885NPC1 3758/4885RAB9A 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.