Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326250 | 0.74 | ALOX5 (0.53) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL17801567 | 0.74 | ALOX5 (0.45) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL2100052 | 0.74 | — | — | |
| SCHEMBL28009434 | 0.73 | ALOX5 (0.49) | ALOX5ALDH1A1POLBHPGDMAPT | |
| Hydrochloric Acid SCHEMBL5352595 | 0.73 | ALOX5 (0.51) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL2100645 | 0.73 | ALOX5 (0.51) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL11234382 | 0.71 | ALDH1A1 (0.50) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL8181893 | 0.71 | EPHX2 (0.41) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL3217675 | 0.70 | ALDH1A1 (0.53) | ALOX5ALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL6565710 | 0.69 | ALDH1A1 (0.41) | ALOX5ALDH1A1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | NATIONAL SCIENCE FOUNDATION | 2020-04-09 | — | — | US | disclosed |
| US-20170360940-A1 | NUCLEOPHILE-TRIGGERED DEGRADABLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | NATIONAL SCIENCE FOUNDATION | 2017-12-21 | — | — | US | disclosed |
| WO-2016090060-A1 | NUCLEOPHILE-TRIGGERED DEGRADBLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360940-A1 | NUCLEOPHILE-TRIGGERED DEGRADABLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | OGG1, MRE11, DNA2 | ALOX5 1036/4885ALDH1A1 1711/4885POLB 82/4885 |
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | MRE11, ENDOD1, DNASE1 | ALOX5 1214/4885ALDH1A1 2338/4885POLB 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.