Diphenylether

Diphenylether

SCHEMBL17801641

O=P(O)(O)OP(=O)(O)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.60
LTA4H P09960 4/20 0.57
TSHR P16473 1/20 0.57
MMP2 P08253 2/20 0.52
CA9 Q16790 2/20 0.52
MMP8 P22894 1/20 0.52
MMP14 P50281 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
FDPS P14324 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PARP10 Q53GL7 1/20 0.47
PGR P06401 1/20 0.46
SRD5A2 P31213 1/20 0.45
AKR1C3 P42330 1/20 0.45
CA2 P00918 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL356479 0.87 LTA4H (0.67) SRCLTA4HTSHRMMP2CA9
Diphenylether SCHEMBL17801642 0.87 LTA4H (0.67) SRCLTA4HTSHRMMP2CA9
Diphenylether SCHEMBL27662442 0.85 LTA4H (0.63) SRCLTA4HTSHRMMP2CA9
Diphenylether SCHEMBL28278866 0.85 LTA4H (0.63) SRCLTA4HTSHRMMP2CA9
Diphenylether SCHEMBL27797017 0.85 LTA4H (0.63) SRCLTA4HTSHRMMP2CA9
Pyrophosphoric Acid SCHEMBL14939154 0.85 AKR1C3 (0.47) SRCLTA4HTSHRMMP2CA9
SCHEMBL8388043 0.82 SRC (0.83) SRCLTA4HTSHRMMP2CA9
Diphenylether SCHEMBL28260818 0.81 LTA4H (0.57) SRCLTA4HTSHRMMP2CA9
Biphenyl SCHEMBL8424826 0.80 ACP3 (0.56) SRCTSHRCA9MMP8MMP14
Pyrophosphoric Acid SCHEMBL10438540 0.80 SRC (0.44) SRCTSHRMMP2CA9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227376-A1 HIGH MELT FLOW POLYETHERIMIDE-SILOXANE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES MADE THEREFROM SABIC Global Technologies B.V. (NL) 2017-10-11 EP claimed
WO-2016089583-A1 HIGH MELT FLOW POLYETHERIMIDE-SILOXANE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES MADE THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-09 WO claimed