Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL10438540

O=P(O)(O)OP(=O)(O)O.c1ccc(Oc2cccc(Oc3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.44
CTNNB1 P35222 1/20 0.41
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
HTT P42858 1/20 0.38
INPPL1 O15357 1/20 0.38
INPP5B P32019 1/20 0.38
INPP5A Q14642 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
PDE3A Q14432 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSPO P30536 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
MMP2 P08253 1/20 0.37
MMP8 P22894 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL28910336 0.91 GAPDH (0.40) SRCCTNNB1LMNAGAAKMT2A
Pyrophosphoric Acid SCHEMBL1199532 0.82 GPR84 (0.38) SRCCTNNB1GPR84MMP2MMP8
Phosphoric Acid SCHEMBL9017459 0.82 GAPDH (0.42) SRCCTNNB1LMNAGAAKMT2A
Pyrophosphoric Acid SCHEMBL10436218 0.81 GPR84 (0.38) SRCCTNNB1GPR84MMP2MMP8
Pyrophosphoric Acid SCHEMBL27988232 0.81 GPR84 (0.38) SRCCTNNB1GPR84MMP2MMP8
Diphenylether SCHEMBL17801641 0.80 SRC (0.60) SRCMMP2MMP8MMP14CA9
SCHEMBL4860340 0.78 CTNNB1 (0.46) CTNNB1LMNAGAAKMT2AHTT
Pyrophosphoric Acid SCHEMBL1244378 0.76 S1PR1 (0.36) SRCLMNAKMT2AL3MBTL1ALDH1A1
Pyrophosphoric Acid SCHEMBL9420720 0.76 LMNA (0.36) LMNAHTTL3MBTL1ALDH1A1GPR84
Biphenyl SCHEMBL8424826 0.75 ACP3 (0.56) SRCALDH1A1HPGDKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356633-A1 Polymer material based on a high-impact polyphenylene ether mixture GENERAL ELECTRIC COMPANY (US) 1990-03-07 EP disclosed