SCHEMBL1780167

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3029390	0.91	GUCY1A1 (0.70)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL4387891	0.91	GUCY1A1 (0.73)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL3034931	0.90	GUCY1A1 (0.69)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL3037767	0.89	GUCY1A1 (0.68)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL1784209	0.89	GUCY1A1 (0.73)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL3037309	0.87	GUCY1A1 (0.66)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL3999061	0.87	GUCY1A1 (0.66)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL3995476	0.86	GUCY1A1 (0.64)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1
	SCHEMBL27799412	0.85	KEAP1 (0.59)	GUCY1A1GUCY1B1KDM4EPOLBMAPT
	SCHEMBL17397674	0.84	GUCY1A1 (0.75)	GUCY1A1GUCY1B1KDM4EHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.