SCHEMBL17802003

SCHEMBL17802003

CN(CCOCCOCCOCCOCCC(=O)O)C(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CTSK P43235 3/20 0.36
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28769254 0.85 CTSK (0.35) BLMPMP22HSD17B10CTSKCHRM2
SCHEMBL17801996 0.84 MEN1 (0.41) BLMPMP22HSD17B10CTSKCHRM2
SCHEMBL29749278 0.83 CTSK (0.36) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL19169986 0.80 CTSK (0.42) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL21224845 0.79 CHRNB2 (0.38) BLMPMP22HSD17B10CTSKCHRM2
SCHEMBL28497762 0.79 CHRNB2 (0.38) BLMPMP22HSD17B10CTSKCHRM2
SCHEMBL3827409 0.76 CTSK (0.36) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL31524126 0.76 BLM (0.48) BLMPMP22HSD17B10CHRM2CHRM4
SCHEMBL30622147 0.76 BLM (0.48) BLMPMP22HSD17B10CHRM2CHRM4
SCHEMBL25969214 0.76 BLM (0.48) BLMPMP22HSD17B10CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903826-B1 BIOMOLECULE CONJUGATES CELGENE CORP (US) 2024-05-08 EP disclosed
EP-4289483-A2 BIOMOLECULE CONJUGATES Celgene Corporation (US) 2023-12-13 EP disclosed
CN-114656483-A Biomolecular conjugates 细胞基因公司 2022-06-24 CN disclosed
EP-3903826-A1 BIOMOLECULE CONJUGATES Celgene Corporation (US) 2021-11-03 EP disclosed
US-10335495-B2 Biomolecule conjugates CELGENE CORPORATION (US) 2019-07-02 US disclosed
US-20170360952-A1 BIOMOLECULE CONJUGATES CELGENE CORPORATION 2017-12-21 US disclosed
EP-3226910-A1 BIOMOLECULE CONJUGATES Celgene Corporation (US) 2017-10-11 EP disclosed
WO-2016090157-A1 BIOMOLECULE CONJUGATES CELGENE CORPORATION (US) 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10335495-B2 Biomolecule conjugates DNPEP, NAPA, NCL BLM 2479/4885PMP22 3680/4885HSD17B10 2325/4885
US-20170360952-A1 BIOMOLECULE CONJUGATES DNPEP, NAPA, NCL BLM 2479/4885PMP22 3680/4885HSD17B10 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.