SCHEMBL19169986

SCHEMBL19169986

CN(CCC(=O)O)C(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.42
PHF8 Q9UPP1 4/20 0.39
KDM2A Q9Y2K7 4/20 0.39
KDM7A Q6ZMT4 2/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
KDM4A O75164 11/20 0.35
KDM4C Q9H3R0 11/20 0.35
KDM5A P29375 1/20 0.35
KDM6B O15054 1/20 0.34
KDM5C P41229 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17801900 0.84 EPHX2 (0.47) PHF8KDM2AKDM7AKDM4AKDM4C
SCHEMBL12393191 0.84 CTSK (0.44) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL12265808 0.80 PHF8 (0.40) PHF8KDM2AKDM7AKDM4AKDM4C
SCHEMBL17802003 0.80 BLM (0.39) CTSKPHF8KDM2ACHRM2CHRM4
SCHEMBL12393190 0.79 CTSK (0.46) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL4198129 0.78 CTSK (0.39) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL13526069 0.77 THRB (0.44) PHF8KDM2AKDM7AKDM4AKDM4C
SCHEMBL8434418 0.77 MAPT (0.43) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL8366044 0.77 CTSK (0.41) CTSKCHRM2CHRM4CHRM5CHRM1
SCHEMBL571376 0.77 CHRM2 (0.40) CTSKCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170210916-A1 SURFACE COATING MATERIAL, COATING FILM, AND HYDROPHILIC OIL REPELLENT MEMBER MITSUBISHI MATERIALS CORPORATION (JP) 2017-07-27 US disclosed