Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.35 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802430 | 0.73 | ALOX15 (0.39) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL17608657 | 0.72 | MGAM (0.48) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL17443543 | 0.69 | KDM4E (0.41) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL4900470 | 0.69 | KDM4E (0.47) | ALOX15ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL2022194 | 0.68 | KDM4E (0.49) | ALOX15ALDH1A1KDM4EKMT2AMGAM | |
| SCHEMBL13313392 | 0.66 | KDM4E (0.46) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL5254858 | 0.66 | KDM4E (0.41) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2175934 | 0.66 | MGAM (0.64) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL698486 | 0.65 | MGAM (0.42) | KDM4EMGAMTDP1 | |
| SCHEMBL1088781 | 0.64 | KDM4E (0.67) | ALOX15KDM4EKMT2AMGAMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226862-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090382-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-06-09 | — | — | WO | disclosed |