Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802429 | 0.73 | ALOX15 (0.39) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL30729983 | 0.72 | TDP1 (0.41) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL31721178 | 0.70 | KDM4E (0.46) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL31721176 | 0.70 | KDM4E (0.46) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2022195 | 0.70 | KDM4E (0.46) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL324668 | 0.69 | KDM4E (0.47) | ALOX15ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL30483401 | 0.67 | NAMPT (0.49) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL4994747 | 0.67 | NAMPT (0.49) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7802908 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL13313392 | 0.66 | KDM4E (0.46) | ALOX15ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226862-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090382-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-06-09 | — | — | WO | disclosed |