Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 5/20 | 0.43 |
| ▸ | CSF1R | P07333 | 5/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 6/20 | 0.43 |
| ▸ | BCR | P11274 | 4/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17812271 | 0.89 | TEK (0.42) | BRAFCSF1RIRAK4NPC1RAB9A | |
| SCHEMBL17811799 | 0.83 | BRAF (0.42) | BRAFCSF1RKITKDRMAPK14 | |
| SCHEMBL17802527 | 0.82 | SMN1; SMN2 (0.44) | BRAFCSF1RKITKDRMAPK14 | |
| SCHEMBL17802477 | 0.82 | TLR8 (0.39) | IRAK4ALDH1A1 | |
| SCHEMBL17802467 | 0.76 | TLR8 (0.40) | IRAK4ALDH1A1 | |
| SCHEMBL16568895 | 0.75 | DGAT1 (0.47) | IRAK4RAB9AMAOAMAOBALDH1A1 | |
| SCHEMBL17802469 | 0.75 | TLR8 (0.39) | ALDH1A1MAPT | |
| SCHEMBL19581840 | 0.73 | MAPT (0.48) | IRAK4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL20548980 | 0.73 | ADORA3 (0.46) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL17803456 | 0.72 | TLR8 (0.39) | IRAK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207466-B | Bicyclic compounds as pest control agents | 拜耳作物科学股份公司 | 2020-09-08 | — | — | CN | disclosed |
| EP-3227274-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2019-07-03 | — | — | EP | disclosed |
| US-10131649-B2 | Bicyclic compounds as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-20 | — | — | US | disclosed |
| US-20170327487-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-3227274-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087421-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131649-B2 | Bicyclic compounds as pest control agents | DDT, BCHE, BAK1 | BRAF 919/4885CSF1R 4877/4885KIT 4659/4885 |
| US-20170327487-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | BRAF 919/4885CSF1R 4877/4885KIT 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.