SCHEMBL1780306

SCHEMBL1780306

CCCC(N)(CN)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
KCNN4 O15554 2/20 0.41
KIF11 P52732 9/20 0.41
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 1/20 0.35
KCNH2 Q12809 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453502 0.89 KCNN4 (0.46) TAAR1KCNN4KIF11CYP2C19HIF1A
SCHEMBL7004942 0.83 TAAR1 (0.52) TAAR1KCNN4KIF11CYP3A4CYP2D6
SCHEMBL28118448 0.82 KCNN4 (0.39) TAAR1KCNN4KIF11CYP2C19HIF1A
SCHEMBL1139107 0.79 CYP2C19 (0.53) KIF11CYP2C19HIF1ACYP3A4CYP2D6
SCHEMBL7125763 0.79 CYP1A2 (0.38) TAAR1KCNN4KIF11KCNH2CYP2D6
SCHEMBL1139315 0.79 CYP2C19 (0.53) KIF11CYP2C19HIF1ACYP3A4CYP2D6
SCHEMBL9425766 0.78 TAAR1 (0.52) TAAR1KCNN4KIF11
SCHEMBL157809 0.78 KCNN4 (0.48) TAAR1KCNN4KIF11CYP2D6
Hydrochloric Acid SCHEMBL9426177 0.77 TAAR1 (0.50) TAAR1KCNN4KIF11CYP2C19CYP3A4
SCHEMBL1261574 0.77 KIF11 (0.44) TAAR1KCNN4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119905295-A Anti-folding flame-retardant data cable and preparation method thereof 杭州兴发科技股份有限公司 2025-04-29 CN claimed
CN-117727496-B Silicon rubber insulation special power cable 源鑫线缆有限公司 2024-07-02 CN claimed
CN-117727496-A Silicon rubber insulation special power cable 源鑫线缆有限公司 2024-03-19 CN claimed
EP-3154937-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM Fina Technology, Inc. (US) 2017-04-19 EP claimed
WO-2015191721-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY, INC. (US) 2015-12-17 WO claimed
CN-119905295-A Anti-folding flame-retardant data cable and preparation method thereof 杭州兴发科技股份有限公司 2025-04-29 CN disclosed
CN-117727496-B Silicon rubber insulation special power cable 源鑫线缆有限公司 2024-07-02 CN disclosed
EP-3154937-B1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY (US) 2024-05-22 EP disclosed
CN-117727496-A Silicon rubber insulation special power cable 源鑫线缆有限公司 2024-03-19 CN disclosed
EP-3096751-B1 12-EPI-PLEUROMUTILINS Nabriva Therapeutics GmbH (AT) 2021-01-06 EP disclosed
CN-105916499-B 12-epi-pleuromutilins 纳布里瓦治疗股份公司 2020-02-18 CN disclosed
US-9701628-B2 12-epi pleuromutilins NABRIVA THERAPEUTICS AG (AT) 2017-07-11 US disclosed
US-8202910-B2 Compositions and methods for treatment of infectious disease SEQUELLA, INC. (US) 2012-06-19 US disclosed
US-20110118307-A1 Compositions and methods for the treatment of infectious diseases GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2011-05-19 US disclosed
US-7842729-B2 Anti tubercular drug: compositions and methods THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2010-11-30 US disclosed
US-20090192173-A1 ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS SEQUELLA, INC. 2009-07-30 US disclosed
US-7456222-B2 Anti tubercular drug: compositions and methods SEQUELLA, INC. (US) 2008-11-25 US disclosed
US-20060148904-A1 Anti tubercular drug: compositions and methods SEQUELLA, INC. 2006-07-06 US disclosed
US-20060020041-A1 Anti tubercular drug: compositions and methods SEQUELLA, INC. 2006-01-26 US disclosed
US-6951961-B2 Methods of use and compositions for the diagnosis and treatment of infectious disease GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2005-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118307-A1 Compositions and methods for the treatment of infectious diseases TERT, C5, ELANE TAAR1 1357/4885KCNN4 4779/4885KIF11 3841/4885
US-20090192173-A1 ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS RIF1, TERT, ELL TAAR1 2139/4885KCNN4 4472/4885KIF11 3858/4885
US-20060148904-A1 Anti tubercular drug: compositions and methods C5, DERA, ELL TAAR1 937/4885KCNN4 4817/4885KIF11 4014/4885
US-20060020041-A1 Anti tubercular drug: compositions and methods C5, DERA, ELL TAAR1 937/4885KCNN4 4817/4885KIF11 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.