Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377714 | 1.00 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL11031727 | 0.98 | IDO1 (0.55) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL2904854 | 0.98 | IDO1 (0.55) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL18725306 | 0.85 | ABCB1 (0.48) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL28854332 | 0.83 | HTR7 (0.49) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL5395739 | 0.82 | SMN1; SMN2 (0.44) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL1279269 | 0.82 | TAAR1 (0.64) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL20913236 | 0.82 | TAAR1 (0.64) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL29447946 | 0.82 | TAAR1 (0.64) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL216572 | 0.80 | SMN1; SMN2 (0.50) | CA1CA2CA12CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2021-03-25 | — | — | US | claimed |
| CN-112538025-A | Preparation method of fluorine-containing compound for hydrophobic surface treatment agent | 湖北福力德鞋业有限责任公司 | 2021-03-23 | — | — | CN | claimed |
| CN-107936012-B | Preparation method of beta-carboline compound for preparing anti-renal fibrosis drug and/or anti-chronic nephrosis drug | 安徽和医天下医药科技有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-107721869-A | A kind of synthetic method of the cyanobenzaldehyde of 2 methoxyl group 4 | 上海雅本化学有限公司 | 2018-02-23 | — | — | CN | claimed |
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2016-08-18 | — | — | US | claimed |
| EP-3049072-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | William Marsh Rice University (US) | 2016-08-03 | — | — | EP | claimed |
| WO-2015048268-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2015-04-02 | — | — | WO | claimed |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2013-12-26 | — | — | US | claimed |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-12-26 | — | — | US | claimed |
| EP-2544535-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | North Carolina Central University (US) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112858-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-09-15 | — | — | WO | claimed |
| WO-2011084503-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |
| WO-2006048727-A1 | PIPERAZINYLPHENALKYL LACTAM/AMINE LIGANDS FOR THE 5HT1B RECEPTOR | PFIZER PRODUCTS INC. (US) | 2006-05-11 | — | — | WO | claimed |
| EP-0831769-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040048-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1996-12-19 | — | — | WO | claimed |
| CN-116813550-B | Indazole derivative, preparation method, pharmaceutical composition and application thereof | Shanghai Pharmaceutical Industry Research Institute Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-122036587-A | Zalutst compound and application thereof in inhibiting MLL1-WDR5 interaction | 暨南大学 | 2026-05-15 | — | — | CN | disclosed |
| US-3970671-A | XANTHENE, PRESSURE SENSITIVE | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1976-07-20 | — | — | US | disclosed |
| US-3947471-A | CHROMOGENIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | CES2, TOP1, GUSB | IDO1 2246/4885TAAR1 3652/4885CHRM2 4740/4885 |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | IDO1 609/4885TAAR1 3261/4885CHRM2 4253/4885 |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, TOP2B | IDO1 616/4885TAAR1 3007/4885CHRM2 4247/4885 |
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | IDO1 609/4885TAAR1 3261/4885CHRM2 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.