SCHEMBL17522133

SCHEMBL17522133

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](COP(=O)(OC)OC)NC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PLA2G4A P47712 4/20 0.46
▸ PLA2G2A P14555 4/20 0.40
▸ CTSK P43235 5/20 0.38
▸ CTSS P25774 1/20 0.37
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SGPL1 O95470 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17522134 0.85 CTSK (0.41) PLA2G4ACTSKCTSSSGPL1
SCHEMBL6404277 0.81 MEN1 (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL19442941 0.81 CA1 (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL6404279 0.81 MEN1 (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL15941659 0.81 PLA2G4A (0.60) PLA2G4AMEN1KMT2A
SCHEMBL15948851 0.81 PLA2G4A (0.60) PLA2G4AMEN1KMT2A
SCHEMBL30905694 0.79 CTSK (0.39) PLA2G4ACTSKCTSSCA1CA2
SCHEMBL20830129 0.74 CA1 (0.40) PLA2G4ACTSKCA1CA2CA7
SCHEMBL17804033 0.74 PLA2G4A (0.48) PLA2G4A
SCHEMBL17522131 0.73 CTSK (0.42) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783562-B2 Phytosphingosine-1-phosphate derivative, preparation method therefor, and composition for preventing and treating hair loss or for growing hair comprising same PHYTOS CO., LTD (KR) 2017-10-10 — — US disclosed
US-9783562-B2 Phytosphingosine-1-phosphate derivative, preparation method therefor, and composition for preventing and treating hair loss or for growing hair comprising same PHYTOS CO., LTD (KR) 2017-10-10 — — US disclosed
US-20160046656-A1 NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME PHYTOS CO., LTD. (KR) 2016-02-18 — — US disclosed
US-20160046656-A1 NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME PHYTOS CO., LTD. (KR) 2016-02-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160046656-A1 NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME SGPL1, DCTPP1, PSAP PLA2G4A 1013/4885PLA2G2A 1231/4885CTSK 3540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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