Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804276 | 0.85 | NR1H4 (0.33) | MAPTMAPK1TDP1SMN1; SMN2TSHR | |
| SCHEMBL20195658 | 0.84 | ALDH1A1 (0.40) | MAPTMAPK1TDP1SMN1; SMN2TSHR | |
| SCHEMBL20195438 | 0.81 | ALDH1A1 (0.42) | MAPTMAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL17788182 | 0.78 | MAPT (0.38) | MAPTMAPK1TDP1SMN1; SMN2TSHR | |
| SCHEMBL17788178 | 0.76 | S1PR4 (0.42) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL17804268 | 0.75 | DRD1 (0.33) | — | |
| SCHEMBL17788177 | 0.74 | KMT2A (0.42) | MAPTMAPK1TDP1LMNANR1H4 | |
| SCHEMBL17788170 | 0.74 | HTR6 (0.37) | MAPTMAPK1TDP1LMNASMN1; SMN2 | |
| SCHEMBL18185031 | 0.74 | TDP1 (0.40) | MAPTMAPK1TDP1LMNASMN1; SMN2 | |
| SCHEMBL18185060 | 0.72 | CACNA1C (0.40) | MAPTMAPK1TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2016-06-08 | — | — | EP | disclosed |