SCHEMBL20195658

SCHEMBL20195658

Cc1ccc(C)c(OCc2c(C3CC3)cccc2[N+](=O)[O-])n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
SSTR4 P31391 3/20 0.36
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
MAPK1 P28482 2/20 0.36
HTR1A P08908 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
CACNA1C Q13936 1/20 0.34
TSHR P16473 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PDK2 Q15119 1/20 0.34
PDK4 Q16654 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195438 0.85 ALDH1A1 (0.42) ALDH1A1SSTR4MAPTMAPK1HTR1A
SCHEMBL17804277 0.84 MAPT (0.34) ALDH1A1MAPTTDP1MAPK1CACNA1C
SCHEMBL20195579 0.81 LMNA (0.44) ALDH1A1MAPTTDP1MAPK1TSHR
SCHEMBL17804276 0.80 NR1H4 (0.33) ALDH1A1MAPTTDP1MAPK1CACNA1C
SCHEMBL17788182 0.78 MAPT (0.38) ALDH1A1MAPTTDP1MAPK1CACNA1C
SCHEMBL18185031 0.77 TDP1 (0.40) ALDH1A1MAPTTDP1MAPK1CACNA1C
SCHEMBL17788178 0.76 S1PR4 (0.42) ALDH1A1MAPTMAPK1SMN1; SMN2MEN1
SCHEMBL17788177 0.75 KMT2A (0.42) ALDH1A1MAPTTDP1MAPK1MEN1
SCHEMBL17788170 0.75 HTR6 (0.37) ALDH1A1MAPTTDP1MAPK1TSHR
SCHEMBL18185060 0.74 CACNA1C (0.40) ALDH1A1MAPTTDP1MAPK1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed