SCHEMBL4088282

SCHEMBL4088282

Nc1ncnc2c1ncn2CCC(CO)CO

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 9/20 0.70
ADORA1 P30542 4/20 0.70
AHCY P23526 8/20 0.63
ADORA2B P29275 1/20 0.61
PI4KA P42356 1/20 0.60
PI4K2B Q8TCG2 1/20 0.60
PI4K2A Q9BTU6 1/20 0.60
PI4KB Q9UBF8 1/20 0.60
ADCY1 Q08828 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10009500 0.93 ADORA2A (0.65) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL13952171 0.92 ADORA2A (0.63) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL5965418 0.87 ADORA2A (0.74) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL987631 0.87 ADORA2A (0.74) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL7745013 0.85 AHCY (0.76) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL12418038 0.83 ADORA2A (0.63) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL8839648 0.83 AHCY (0.68) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL11487766 0.83 ADORA2A (0.71) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL984944 0.83 ADORA2A (1.00) ADORA2AADORA1AHCYADORA2BPI4KA
SCHEMBL29459142 0.83 ADORA2A (1.00) ADORA2AADORA1AHCYADORA2BPI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115803033-A Modified adenosine nucleosides for the treatment of viral infections 詹皮特罗·亚切蒂尼 2023-03-14 CN disclosed
US-20090203636-A1 Prevention and Treatment of Cancer and Other Diseases ALT SOLUTIONS, INC. 2009-08-13 US disclosed
US-20090203636-A1 Prevention and Treatment of Cancer and Other Diseases ALT SOLUTIONS, INC. 2009-08-13 US disclosed
US-20090203636-A1 Prevention and Treatment of Cancer and Other Diseases ALT SOLUTIONS, INC. 2009-08-13 US disclosed
EP-2001488-A2 PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES Alt Solutions, Inc. (US) 2008-12-17 EP disclosed
WO-2007106561-A2 PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES ALT SOLUTIONS, INC. (US) 2007-09-20 WO disclosed
WO-2007106561-A2 PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES ALT SOLUTIONS, INC. (US) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203636-A1 Prevention and Treatment of Cancer and Other Diseases TERT, POLRMT, RNASE1 ADORA2A 1461/4885ADORA1 2194/4885AHCY 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.