Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.80 |
| ▸ | CTSS | P25774 | 1/20 | 0.80 |
| ▸ | CTSK | P43235 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TACR1 | P25103 | 3/20 | 0.65 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | TACR3 | P29371 | 1/20 | 0.61 |
| ▸ | CCKBR | P32239 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | NMBR | P28336 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419170 | 0.90 | CTSL (0.77) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL30375072 | 0.90 | CTSL (0.80) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL15145404 | 0.90 | CTSL (0.77) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL21269082 | 0.90 | CTSL (0.77) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL15145364 | 0.90 | CTSL (0.77) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL21286953 | 0.90 | CTSL (0.77) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL9834534 | 0.90 | CTSL (0.80) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27871524 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27902245 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL9025972 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803047-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-10-31 | — | — | US | disclosed |
| US-9803047-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170158808-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | UNIV NEW YORK STATE RES FOUND (US) | 2017-06-08 | — | — | US | disclosed |
| US-20170158808-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | UNIV NEW YORK STATE RES FOUND (US) | 2017-06-08 | — | — | US | disclosed |
| US-9624338-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624338-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160159972-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158808-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | PARG, PARN, TRPC4 | CTSL 3470/4885CTSS 2089/4885CTSK 3058/4885 |
| US-20160159972-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | PARG, PARN, TRPC4 | CTSL 3470/4885CTSS 2089/4885CTSK 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.