SCHEMBL17809088

SCHEMBL17809088

Cn1cc([C@@H]2OC(COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DNPH1 O43598 1/20 0.53
▸ UMPS P11172 3/20 0.49
▸ P2RY6 Q15077 5/20 0.48
▸ EIF4E P06730 2/20 0.47
▸ FBP1 P09467 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18118158 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL15836223 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL17789097 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL14929195 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL10133476 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL14946152 1.00 DNPH1 (0.53) DNPH1UMPSP2RY6EIF4EFBP1
SCHEMBL26115033 0.91 P2RY6 (0.52) P2RY6
SCHEMBL14929352 0.90 DNPH1 (0.43) DNPH1UMPSP2RY6EIF4E
SCHEMBL18574182 0.90 DNPH1 (0.43) DNPH1UMPSP2RY6EIF4E
SCHEMBL14946382 0.90 DNPH1 (0.43) DNPH1UMPSP2RY6EIF4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170252461-A1 HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA MODERNATX, INC. 2017-09-07 — — US disclosed
US-9572897-B2 Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins MODERNATX, INC. (US) 2017-02-21 — — US disclosed
US-20160158385-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS ARES CAPITAL CORPORATION, AS AGENT 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160158385-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS POLRMT, POLN, PHAX DNPH1 3443/4885UMPS 1052/4885P2RY6 3989/4885
US-20170252461-A1 HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA RNGTT, NSUN3, CPSF6 DNPH1 1742/4885UMPS 329/4885P2RY6 3799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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