Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17811635 | 0.91 | NOS3 (0.33) | — | |
| SCHEMBL16455143 | 0.78 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL17811634 | 0.78 | GRM5 (0.33) | GRM5 | |
| SCHEMBL22833834 | 0.77 | NOS3 (0.36) | RIPK1 | |
| SCHEMBL26076020 | 0.77 | HRH4 (0.33) | GRM5 | |
| SCHEMBL19228217 | 0.75 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL24252084 | 0.72 | KCNH2 (0.33) | — | |
| SCHEMBL22309037 | 0.71 | HRH4 (0.32) | — | |
| SCHEMBL20221858 | 0.71 | RIPK1 (0.55) | RIPK1GRM5 | |
| SCHEMBL25596570 | 0.71 | MAPK13 (0.30) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605004-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| US-9605004-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| US-20160168126-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168126-A1 | CHEMICAL COMPOUNDS | RDX, CBR3, RRS1 | RIPK1 1493/4885GRM5 2212/4885 |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | RDX, CBR3, RRS1 | RIPK1 1576/4885GRM5 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.