SCHEMBL1781163

SCHEMBL1781163

[c]1ccccc1-c1cc2ccccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.55
NPC1 O15118 4/20 0.55
KDM4E B2RXH2 4/20 0.49
MAPT P10636 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
CASP3 P42574 2/20 0.49
SENP8 Q96LD8 2/20 0.49
SENP7 Q9BQF6 2/20 0.49
SENP6 Q9GZR1 2/20 0.49
CYP1A2 P05177 2/20 0.49
CHEK1 O14757 1/20 0.49
KDR P35968 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
ITK Q08881 2/20 0.45
CYP19A1 P11511 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11549930 0.81 RAB9A (0.54) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL22573025 0.81 RAB9A (0.50) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL374022 0.79 RAB9A (0.74) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL29631691 0.79 RAB9A (0.74) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL11558539 0.77 RAB9A (0.57) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL4689765 0.74 RAB9A (0.52) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL3135756 0.73 NPC1 (0.71) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL7917255 0.73 RAB9A (0.50) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL690118 0.73 CYP19A1 (0.53) RAB9ANPC1KDM4EMAPTMEN1
SCHEMBL4031802 0.73 RAB9A (0.50) RAB9ANPC1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114361341-A Laminated image pickup device and image pickup module 索尼公司 2022-04-15 CN claimed
CN-107534050-B Image sensor, laminated image pickup device, and image pickup module 索尼公司 2021-12-14 CN claimed
CN-112670425-A Organic light emitting device 三星显示有限公司 2021-04-16 CN claimed
CN-111316459-A Photoelectric conversion element and imaging device 索尼公司 2020-06-19 CN claimed
US-10566548-B2 Image sensor, stacked imaging device and imaging module SONY CORPORATION (JP) 2020-02-18 US claimed
EP-3300114-B1 IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE SONY CORP (JP) 2020-01-08 EP claimed
US-20180114926-A1 IMAGE SENSOR, STACKED IMAGING DEVICE AND IMAGING MODULE SONY CORPORATION (JP) 2018-04-26 US claimed
EP-3300114-A1 IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE Sony Corporation (JP) 2018-03-28 EP claimed
EP-2144889-B1 QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS DAC SRL (IT) 2012-08-29 EP claimed
US-20110118258-A1 QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS DAC SRL (IT) 2011-05-19 US claimed
EP-2144889-A2 QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS DAC S.r.l. (IT) 2010-01-20 EP claimed
WO-2008142720-A2 QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS DAC SRL (IT) 2008-11-27 WO claimed
EP-0770079-B1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2003-02-12 EP claimed
US-20020107251-A1 Heterobicyclic derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-08-08 US claimed
US-6426345-B1 PHOSPHODIESTERASE INHIBITORS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-07-30 US claimed
EP-0770079-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-02 EP claimed
WO-1996001825-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-01-25 WO claimed
US-20230201161-A1 Combination comprising HDAC inhibitor, LAG-3 inhibitor and a PD-1 inhibitor or PD-L1 inhibitor for cancer treatment 4SC AG (DE) 2023-06-29 US disclosed
EP-0770079-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-02 EP disclosed
WO-1996001825-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118258-A1 QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS HSP90AB1, HSP90AA1, HSP90B1 RAB9A 243/4885NPC1 3064/4885KDM4E 2835/4885
US-20020107251-A1 Heterobicyclic derivatives ARSA, ARRB1, SULT2A1 RAB9A 1092/4885NPC1 875/4885KDM4E 2663/4885
US-20230201161-A1 Combination comprising HDAC inhibitor, LAG-3 inhibitor and a PD-1 inhibitor or PD-L1 inhibitor for cancer treatment HDAC1, HDAC3, HDAC11 RAB9A 1283/4885NPC1 3699/4885KDM4E 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.