SCHEMBL1781189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1117942	0.89	HTT (0.44)	RAB9ANPC1SMN1; SMN2MEN1KMT2A
	SCHEMBL1781491	0.89	PIK3CG (0.42)	RAB9ANPC1SMN1; SMN2TP53LMNA
	SCHEMBL4550899	0.87	TSHR (0.40)	RAB9ANPC1SMN1; SMN2MEN1KMT2A
	SCHEMBL1117979	0.83	PIK3CD (0.40)	RAB9ANPC1SMN1; SMN2MEN1KMT2A
	SCHEMBL1118068	0.82	CSNK2A2 (0.38)	RAB9ANPC1SMN1; SMN2MEN1KMT2A
	SCHEMBL1117877	0.81	POLB (0.42)	RAB9ANPC1SMN1; SMN2PI4KBKDM4E
	SCHEMBL1782049	0.80	PIK3CG (0.38)	RAB9ANPC1SMN1; SMN2TP53LMNA
	SCHEMBL1117849	0.80	HDAC1 (0.39)	RAB9ANPC1SMN1; SMN2PI4KBLMNA
	SCHEMBL2671316	0.79	HDAC1 (0.35)	NPC1MAPTKDM4EALDH1A1HDAC1
	SCHEMBL1780133	0.79	HCAR3 (0.39)	RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.