SCHEMBL1117877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1117909	0.89	EPHX2 (0.39)	PIK3CAPIK3CGNPC1RAB9API4KB
	SCHEMBL1117967	0.83	LCK (0.37)	PIK3CGPI4KBPI4KALCKNAMPT
	SCHEMBL1781491	0.82	PIK3CG (0.42)	POLBPIK3CAPIK3CGNPC1RAB9A
	SCHEMBL1781189	0.81	RAB9A (0.38)	POLBPIK3CAPIK3CGNPC1RAB9A
	SCHEMBL1117942	0.80	HTT (0.44)	POLBNPC1RAB9AKDM4EALDH1A1
	SCHEMBL4550899	0.80	TSHR (0.40)	POLBPIK3CGNPC1RAB9API4KB
	SCHEMBL1781560	0.79	PIK3CA (0.36)	PIK3CAPIK3CGNPC1RAB9API4KB
	SCHEMBL1118068	0.78	CSNK2A2 (0.38)	POLBNPC1RAB9AKDM4EL3MBTL1
	SCHEMBL1783723	0.78	OGA (0.34)	PIK3CAPIK3CGPI4KBPIK3CDPIK3CB
	SCHEMBL1117926	0.77	HCAR3 (0.37)	PIK3CGNPC1RAB9API4KBPI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.