SCHEMBL1781244

SCHEMBL1781244

C1=NCCCNCCNCCCNC1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7616222 0.98 CXCR4 (0.38) CXCR4SMN1; SMN2ALDH1A1
SCHEMBL1782169 0.93
SCHEMBL2260970 0.93
SCHEMBL16100819 0.85
SCHEMBL16100820 0.85
SCHEMBL16583914 0.83
SCHEMBL1780706 0.82 HIF1A (0.33)
SCHEMBL1781456 0.82 HIF1A (0.33)
SCHEMBL625882 0.82 HIF1A (0.33)
SCHEMBL12095338 0.82 HIF1A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234720-A Radiolabeled fibroblast activation protein ligand 菲罗化学股份公司 2024-06-21 CN claimed
CN-114832119-B Radioactive gel microsphere and preparation method and application thereof 苏州大学 2024-02-09 CN claimed
CN-117460528-A anti-CLDN 18.2 antibody conjugates 苏州创胜医药集团有限公司 2024-01-26 CN claimed
EP-4294441-A1 ANTI-CLDN18.2 ANTIBODY CONJUGATES Suzhou Transcenta Therapeutics Co., Ltd. (CN) 2023-12-27 EP claimed
CN-116917278-A Divalent fibroblast activation protein ligands for targeted delivery applications 菲罗化学股份公司 2023-10-20 CN claimed
CN-115721742-A Radioactive immunoconjugates and their use for bone marrow pretreatment or treatment of bone marrow related diseases 塞拉法尔目有限责任公司 2023-03-03 CN claimed
CN-115335370-A Fibroblast activation protein ligands for targeted delivery applications 菲洛谢姆股份公司 2022-11-11 CN claimed
WO-2022174809-A1 ANTI-CLDN18.2 ANTIBODY CONJUGATES Suzhou Transcenta Therapeutics Co., Ltd. (CN) 2022-08-25 WO claimed
CN-114832119-A Radioactive gel microsphere and preparation method and application thereof 苏州大学 2022-08-02 CN claimed
US-11000604-B2 Reagent for site-selective bioconjugation of proteins or antibodies RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2021-05-11 US claimed
CN-112601740-A Radioactive compounds for the treatment of melanoma and uses thereof 全南大学校产学协力团 2021-04-02 CN claimed
US-20200397928-A1 REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK 2020-12-24 US claimed
CN-111808161-A Method for radiolabeling biological compounds 北京大学 2020-10-23 CN claimed
US-7205385-B2 magnetic resonance imaging agents; poly(amino acid-imaging agent) product can be obtained in high purity without a rigorous purification since all impurities are removed at the monomer synthesis stage GENERAL ELECTRIC COMPANY (US) 2007-04-17 US claimed
EP-0584256-B1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR DETECTING AND LOCALIZING TISSUES HAVING NEUROKININE 1 RECEPTORS MALLINCKRODT MEDICAL INC (US) 1999-11-10 EP claimed
WO-1995026206-A1 METHOD FOR PREPARING RADIONUCLIDE-LABELED CHELATING AGENT-LIGAND COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-05 WO claimed
US-5273743-A A compound made up of three different Fab'-like fragments linked by a bis- or trissuccinimidyl moiety; retention of antigen binding acitivity HYBRITECH INCORPORATED (US) 1993-12-28 US claimed
US-20260021213-A1 METHOD FOR PRODUCING FC-CONTAINING MOLECULE MODIFYING REAGENT NIHON MEDI-PHYSICS CO., LTD. (JP) 2026-01-22 US disclosed
EP-0433312-A1 CARRIER SYSTEM AND METHOD FOR ENHANCEMENT OF MAGNETIC RESONANCE IMAGING THE UNIVERSITY OF CONNECTICUT (US) 1991-06-26 EP disclosed
WO-1990001900-A1 CARRIER SYSTEM AND METHOD FOR ENHANCEMENT OF MAGNETIC RESONANCE IMAGING THE UNIVERSITY OF CONNECTICUT (US) 1990-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200397928-A1 REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES MRPL21, TFRC, ARGLU1 CXCR4 2100/4885SMN1; SMN2 2820/4885ALDH1A1 835/4885
US-11000604-B2 Reagent for site-selective bioconjugation of proteins or antibodies MRPL21, TFRC, ARGLU1 CXCR4 2100/4885SMN1; SMN2 2820/4885ALDH1A1 835/4885
US-20260021213-A1 METHOD FOR PRODUCING FC-CONTAINING MOLECULE MODIFYING REAGENT PTMS, FCGR1A, F13B CXCR4 1349/4885SMN1; SMN2 4013/4885ALDH1A1 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.