Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640158 | 0.97 | PIK3CA (0.49) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805231 | 0.97 | PIK3CA (0.49) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17812842 | 0.95 | PIK3CA (0.46) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805260 | 0.93 | PIK3CA (0.45) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805254 | 0.92 | NPC1 (0.46) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805219 | 0.91 | PIK3CA (0.46) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805252 | 0.90 | PIK3CA (0.46) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805188 | 0.89 | PIK3CA (0.43) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17812867 | 0.86 | NPC1 (0.39) | PIK3CAPIK3CDMTORPIK3CBPIK3CG | |
| SCHEMBL17805201 | 0.86 | CYP2A6 (0.52) | PIK3CAPIK3CDMTORPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10593884-B2 | Organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-20180006235-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| US-9842999-B2 | Benzotriazole derivative and an organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2017-12-12 | — | — | US | disclosed |
| US-9842999-B2 | Benzotriazole derivative and an organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2017-12-12 | — | — | US | disclosed |
| US-20170346009-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SFC CO., LTD. (KR) | 2017-11-30 | — | — | US | disclosed |
| US-20170346009-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SFC CO., LTD. (KR) | 2017-11-30 | — | — | US | disclosed |
| WO-2016111254-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | 保土谷化学工業株式会社 | 2016-07-14 | — | — | WO | disclosed |
| US-20160164001-A1 | A BENZOTRIAZOLE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160164001-A1 | A BENZOTRIAZOLE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10593884-B2 | Organic electroluminescent device | AHR, SLC18A1, KCNH1 | PIK3CA 3361/4885PIK3CD 3880/4885MTOR 2594/4885 |
| US-20180006235-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | AHR, SLC18A1, KCNH1 | PIK3CA 3361/4885PIK3CD 3880/4885MTOR 2594/4885 |
| US-20160164001-A1 | A BENZOTRIAZOLE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE | AHR, ARNT, NAT1 | PIK3CA 4809/4885PIK3CD 4758/4885MTOR 3707/4885 |
| US-20170346009-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | AHR, SLC18A1, ARNT | PIK3CA 3322/4885PIK3CD 3842/4885MTOR 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.