Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 4/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976533 | 0.97 | POLB (0.35) | POLBMAPK1SMN1; SMN2TLR7HDAC3 | |
| SCHEMBL16252079 | 0.92 | TLR7 (0.34) | TLR7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL178263 | 0.85 | LMNA (0.35) | POLBMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL203415 | 0.82 | LMNA (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21524641 | 0.80 | LMNA (0.31) | LMNAPTGS1EPHX2PTGS2 | |
| SCHEMBL21297662 | 0.80 | POLB (0.39) | POLBMAPK1SMN1; SMN2TLR7HDAC3 | |
| SCHEMBL19062963 | 0.79 | PTPN1 (0.38) | PTGS2 | |
| SCHEMBL19976571 | 0.78 | PTPN1 (0.36) | PTGS2 | |
| SCHEMBL15392544 | 0.78 | — | — | |
| SCHEMBL16252279 | 0.77 | PTPN1 (0.35) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-9051263-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | POLB 4597/4885MAPK1 1978/4885SMN1; SMN2 3589/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | POLB 4597/4885MAPK1 1978/4885SMN1; SMN2 3589/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | POLB 4597/4885MAPK1 1978/4885SMN1; SMN2 3589/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | POLB 4597/4885MAPK1 1978/4885SMN1; SMN2 3589/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | POLB 4073/4885MAPK1 1363/4885SMN1; SMN2 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.