Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264898 | 0.99 | MGLL (0.46) | MGLLPOLBHSD17B10TSHRPTGS1 | |
| SCHEMBL12284024 | 0.93 | MGLL (0.51) | MGLLPOLBHSD17B10TSHRPTGS1 | |
| SCHEMBL17486903 | 0.93 | MGLL (0.51) | MGLLPOLBHSD17B10TSHRPTGS1 | |
| SCHEMBL12529901 | 0.92 | MGLL (0.46) | MGLLPOLBHSD17B10PTGS1PTGS2 | |
| SCHEMBL18893611 | 0.92 | MGLL (0.46) | MGLLPOLBHSD17B10TSHRPTGS1 | |
| SCHEMBL19401814 | 0.90 | MGLL (0.49) | MGLLPOLBHSD17B10PTGS1PTGS2 | |
| SCHEMBL17833093 | 0.90 | MGLL (0.49) | MGLLPOLBHSD17B10PTGS1PTGS2 | |
| SCHEMBL19318350 | 0.90 | MGLL (0.49) | MGLLPOLBHSD17B10PTGS1PTGS2 | |
| SCHEMBL15148264 | 0.90 | MGLL (0.49) | MGLLPOLBHSD17B10PTGS1PTGS2 | |
| SCHEMBL26519953 | 0.90 | MGLL (0.49) | MGLLPOLBHSD17B10TSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327541-A1 | METHODS FOR SYNTHESIZING alpha4ß7 PEPTIDE ANTAGONISTS | PROTAGONIST THERAPEUTICS, INC. | 2017-11-16 | — | — | US | disclosed |
| US-9518091-B2 | A4B7 peptide monomer and dimer antagonists | PROTAGONIST THERAPEUTICS, INC. | 2016-12-13 | — | — | US | disclosed |
| US-20160159862-A1 | NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS | PROTAGONIST THERAPEUTICS, INC. | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159862-A1 | NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS | EPCAM, VCAM1, ITGB7 | MGLL 4593/4885POLB 4300/4885HSD17B10 3977/4885 |
| US-20170327541-A1 | METHODS FOR SYNTHESIZING alpha4ß7 PEPTIDE ANTAGONISTS | PSMA7, PSMA4, IL4 | MGLL 4882/4885POLB 2290/4885HSD17B10 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.