Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455580 | 1.00 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17808225 | 0.84 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17808229 | 0.84 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL18699192 | 0.80 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL16455757 | 0.74 | PDE3B (0.37) | ALDH1A1ARCYP1A2CYP2C19ASPH | |
| SCHEMBL16454235 | 0.74 | ASPH (0.35) | KDM4EALDH1A1GLACYP1A2CYP2C19 | |
| SCHEMBL16455734 | 0.72 | GABRA1 (0.31) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17797756 | 0.72 | GABRA1 (0.31) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17797764 | 0.72 | GABRA1 (0.31) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL27743600 | 0.72 | ASPH (0.43) | KDM4EALDH1A1GLACYP2C19ASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |
| US-20160159767-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159767-A1 | CHEMICAL COMPOUNDS | DDT, CBR3, CYP1B1 | GABRA1 2809/4885GABRG2 2929/4885GABRB3 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.