Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808229 | 0.87 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17808225 | 0.87 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17813810 | 0.80 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL16455580 | 0.80 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL18699191 | 0.72 | MAPT (0.37) | ARGAAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17816233 | 0.65 | CYP1A2 (0.41) | ARGAAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17797764 | 0.64 | GABRA1 (0.31) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17808248 | 0.64 | ASPH (0.33) | — | |
| SCHEMBL17808249 | 0.64 | PDE3B (0.35) | — | |
| SCHEMBL18699194 | 0.63 | IDO1 (0.41) | ARALDH1A1L3MBTL1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |