Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808350 | 0.89 | TSHR (0.43) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16429645 | 0.85 | TSHR (0.56) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16429651 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL16429545 | 0.80 | ALDH1A1 (0.55) | MAPTALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL17808360 | 0.80 | TSHR (0.49) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL396552 | 0.75 | TSHR (0.69) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29617021 | 0.75 | TSHR (0.80) | TSHRMAPTALDH1A1HSD17B10RAB9A | |
| SCHEMBL3683272 | 0.75 | TSHR (0.80) | TSHRMAPTALDH1A1HSD17B10RAB9A | |
| Bicarbonate SCHEMBL5706047 | 0.74 | TSHR (0.62) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| Bicarbonate SCHEMBL27449726 | 0.74 | TSHR (0.67) | TSHRMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876182-B2 | Thieno-containing compounds and processes and uses thereof | UNIVERSITY OF OREGON (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | UNIVERSITY OF OREGON (US) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | TERT, TES, DDT | TSHR 981/4885MAPT 4115/4885ALDH1A1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.