SCHEMBL17813124

SCHEMBL17813124

O=Nc1ccc(C2(c3ccc(N=O)cc3)C(=O)Nc3ccccc32)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
CHRM2 P08172 1/20 0.66
ADORA3 P0DMS8 1/20 0.66
KCNH2 Q12809 1/20 0.66
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
XBP1 P17861 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
GAA P10253 7/20 0.45
MGAM O43451 5/20 0.45
SI P14410 5/20 0.45
MGAM2 Q2M2H8 5/20 0.45
PDK2 Q15119 1/20 0.44
PDK4 Q16654 1/20 0.44
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.38
MAPK1 P28482 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17814219 0.93 CHRM2 (0.80) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL17813127 0.93 LMNA (0.59) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL2715686 0.82 LMNA (1.00) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL9342160 0.79 LMNA (0.73) LMNACHRM2ADORA3KCNH2MAPT
Oxyphenisatine SCHEMBL239513 0.79 CHRM2 (1.00) LMNACHRM2ADORA3KCNH2MAPT
Oxyphenisatine SCHEMBL35387956 0.79 CHRM2 (1.00) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL25340217 0.78 LMNA (0.76) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL2716060 0.77 CHRM2 (0.93) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL22632192 0.77 LMNA (0.80) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL11361033 0.75 CHRM2 (0.69) LMNACHRM2ADORA3KCNH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017005677-A1 GALVANIZED COMPONENT WITH HIGH HEAT DISTORTION RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2017-01-12 WO disclosed
WO-2017005682-A1 POLYCARBONATE COMPOSITIONS FOR GALVANIC APPLICATIONS HAVING A HIGH REQUIREMENT FOR HEAT DISTORTION POINT COVESTRO DEUTSCHLAND AG (DE) 2017-01-12 WO disclosed
WO-2016087480-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSING BEHAVIOUR CONTAINING PE-WAX COVESTRO DEUTSCHLAND AG (DE) 2016-06-09 WO disclosed
WO-2016087294-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTERS COVESTRO DEUTSCHLAND AG (DE) 2016-06-09 WO disclosed