Sugi Predict

Sugi Predict / Compounds / Chlorobenzene

Chlorobenzene

Chlorobenzene

SCHEMBL1781430

Clc1ccccc1.O=C(OO)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.54
▸ F2 P00734 1/20 0.54
▸ CES2 O00748 1/20 0.54
▸ CES1 P23141 1/20 0.54
▸ TSHR P16473 5/20 0.50
▸ KMT2A Q03164 4/20 0.47
▸ MAPT P10636 3/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ TDP1 Q9NUW8 3/20 0.45
▸ PARP1 P09874 2/20 0.45
▸ TP53 P04637 2/20 0.45
▸ POLB P06746 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ PMP22 Q01453 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ PARP10 Q53GL7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL27464901 0.96 CES2 (0.59) LMNAF2CES2CES1TSHR
Hydrogen Peroxide SCHEMBL11489043 0.89 LMNA (0.67) LMNAF2CES2CES1TSHR
Benzene SCHEMBL10686034 0.89 LMNA (0.67) LMNAF2CES2CES1TSHR
SCHEMBL1816 0.89 LMNA (0.67) LMNAF2CES2CES1TSHR
Hydrogen Peroxide SCHEMBL2929887 0.89 LMNA (0.67) LMNAF2CES2CES1TSHR
SCHEMBL27265493 0.89 LMNA (0.67) LMNAF2CES2CES1TSHR
Benzoyl Peroxide SCHEMBL10457039 0.88 LMNA (0.63) LMNAF2CES2CES1TSHR
SCHEMBL10664817 0.88 PARP1 (0.58) LMNAF2KMT2ASMN1; SMN2TDP1
Chloromethane SCHEMBL27484052 0.86 TSHR (0.60) LMNAF2CES2CES1TSHR
Ammonia Solution, Strong SCHEMBL3267856 0.86 LMNA (0.64) LMNAF2CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110114185-A1 PHOTOELECTRIC CONVERSION ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 — — US disclosed
US-20100201259-A1 COMPOUND AND METHOD FOR PRODUCING THE SAME, AND INK COMPOSITION, THIN FILM, ORGANIC TRANSISTOR AND ORGANIC ELECTROLUMINESCENCE DEVICE, EACH USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-12 — — US disclosed
EP-2180013-A1 COMPOUND, METHOD FOR PRODUCING THE SAME, INK COMPOSITION USING THE COMPOUND, THIN FILM, ORGANIC TRANSISTOR, AND ORGANIC ELECTROLUMINESCENT DEVICE Sumitomo Chemical Company, Limited (JP) 2010-04-28 — — EP disclosed
US-20080312404-A1 Novel diepoxides and epoxy resins PEWS R GARTH 2008-12-18 — — US disclosed
US-7462728-B2 Diepoxide derivatives of N,N*-disubstituted disulfonamides PEWS R GARTH 2008-12-09 — — US disclosed
US-20060128978-A1 Diepoxide derivatives of N, N*-disubstituted disulfonamides PEWS R G 2006-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100201259-A1 COMPOUND AND METHOD FOR PRODUCING THE SAME, AND INK COMPOSITION, THIN FILM, ORGANIC TRANSISTOR AND ORGANIC ELECTROLUMINESCENCE DEVICE, EACH USING THE SAME BMI1, RIF1, TERT LMNA 2771/4885F2 971/4885CES2 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.