Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385937 | 0.76 | — | — | |
| SCHEMBL19076097 | 0.69 | BCHE (0.31) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL17936985 | 0.68 | LMNA (0.37) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL19727095 | 0.68 | DAO (0.32) | — | |
| SCHEMBL9375081 | 0.67 | HLCS (0.33) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL14627580 | 0.66 | CYP3A4 (0.37) | ALDH1A1 | |
| SCHEMBL21944971 | 0.66 | MAN2B1 (0.32) | — | |
| SCHEMBL19733853 | 0.66 | CYP19A1 (0.32) | — | |
| SCHEMBL17936975 | 0.61 | MAOA (0.40) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL6232304 | 0.60 | LMNA (0.49) | KDM4EMEN1ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228616-A1 | PYRIDINE DERIVATIVES | Astellas Pharma Inc. (JP) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016088864-A1 | PYRIDINE DERIVATIVE | アステラス製薬株式会社 | 2016-06-09 | — | — | WO | disclosed |