Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816134 | 0.94 | RARA (0.36) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816156 | 0.94 | RARA (0.36) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816078 | 0.94 | RARA (0.36) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816077 | 0.94 | RARA (0.36) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816136 | 0.91 | NPC1 (0.44) | MAOBNPC1RAB9ALMNAKCNQ3 | |
| SCHEMBL17784050 | 0.91 | RARA (0.37) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816122 | 0.86 | NPC1 (0.47) | MAPTMAOBNPC1RAB9AKCNQ3 | |
| SCHEMBL17816181 | 0.85 | DGAT1 (0.34) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816084 | 0.85 | CYP1A2 (0.37) | RARARARBRARGTP53MAPT | |
| SCHEMBL17816080 | 0.85 | MAPT (0.40) | RARARARBRARGTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089990-A1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | WO | disclosed |