Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816184 | 0.91 | NPC1 (0.42) | DGAT1ITGB3ITGA2BSOAT1MAOA | |
| SCHEMBL17784015 | 0.91 | DGAT1 (0.37) | DGAT1ITGB3ITGA2BSOAT1RARA | |
| SCHEMBL17816187 | 0.87 | NPC1 (0.45) | DGAT1MAOATP53MAPTMAOB | |
| SCHEMBL17816135 | 0.85 | RARA (0.35) | DGAT1RARARARBRARGKDM1A | |
| SCHEMBL21991658 | 0.85 | DGAT1 (0.40) | DGAT1ITGB3ITGA2BSOAT1RARA | |
| SCHEMBL17792189 | 0.85 | DGAT1 (0.40) | DGAT1ITGB3ITGA2BSOAT1RARA | |
| SCHEMBL17784130 | 0.83 | NPC1 (0.45) | DGAT1ITGB3ITGA2BSOAT1MAOA | |
| SCHEMBL17816156 | 0.83 | RARA (0.36) | DGAT1SOAT1RARARARBRARG | |
| SCHEMBL17816078 | 0.83 | RARA (0.36) | DGAT1SOAT1RARARARBRARG | |
| SCHEMBL17816134 | 0.83 | RARA (0.36) | DGAT1SOAT1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089990-A1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | WO | disclosed |