Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 17/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454226 | 0.84 | KMT2A (0.47) | ANO1MEN1KMT2AGABRA1 | |
| SCHEMBL17816257 | 0.83 | NPC1 (0.40) | NPC1PKMRAB9AANO1MEN1 | |
| SCHEMBL16454215 | 0.82 | GABRA1 (0.46) | ANO1KMT2AGABRA1 | |
| SCHEMBL17800712 | 0.79 | NPC1 (0.39) | NPC1PKMRAB9AANO1MEN1 | |
| SCHEMBL14094489 | 0.72 | BAZ2B (0.43) | NPC1RAB9AGABRA1 | |
| SCHEMBL21198407 | 0.72 | ANO1 (0.56) | NPC1PKMRAB9AANO1MEN1 | |
| SCHEMBL17298866 | 0.71 | CNR2 (0.40) | GABRA1 | |
| SCHEMBL280264 | 0.71 | P2RX7 (0.59) | KMT2A | |
| SCHEMBL30252481 | 0.71 | P2RX7 (0.59) | KMT2A | |
| SCHEMBL21198323 | 0.69 | ANO1 (0.54) | ANO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159781-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159781-A1 | CHEMICAL COMPOUNDS | DDT, CBR3, CYP1B1 | NPC1 4651/4885PKM 181/4885RAB9A 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.