SCHEMBL17816490

SCHEMBL17816490

CCC(=O)N(CCN)CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
LMNA P02545 2/20 0.34
TSHR P16473 2/20 0.34
BLM P54132 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ALOX15 P16050 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
CYP2C19 P33261 1/20 0.34
ADRA1A P35348 1/20 0.34
DRD3 P35462 1/20 0.34
PMP22 Q01453 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12581441 0.85 MEN1 (0.32) KMT2A
SCHEMBL260576 0.85 MEN1 (0.32) KMT2A
SCHEMBL12347474 0.85 MEN1 (0.32) KMT2A
SCHEMBL16297673 0.84 ALDH1A1 (0.37) FFAR3TDP1LMNATSHRALOX15
SCHEMBL8045363 0.83 ALDH1A1 (0.36) TDP1
SCHEMBL5080836 0.83 CA12 (0.43) FFAR3TDP1EYA2APPACE
SCHEMBL6444629 0.82 FFAR3 (0.47) FFAR3TDP1EYA2APPACE
SCHEMBL8602002 0.80 FFAR3 (0.45) FFAR3TDP1EYA2APPACE
SCHEMBL12933034 0.79 TDP1 (0.36) TDP1EYA2APPACELMNA
SCHEMBL24312108 0.79 CACNA2D1 (0.36) TDP1EYA2APPACELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170309842-A1 SELF-ASSEMBLED PEPTIDE NUCLEIC ACIDS TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2017-10-26 US disclosed
US-9741948-B2 Self-assembled peptide nucleic acids TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2017-08-22 US disclosed
US-20160164010-A1 SELF-ASSEMBLED PEPTIDE NUCLEIC ACIDS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160164010-A1 SELF-ASSEMBLED PEPTIDE NUCLEIC ACIDS RNGTT, CGAS, SARNP FFAR3 3460/4885TDP1 78/4885EYA2 1080/4885
US-20170309842-A1 SELF-ASSEMBLED PEPTIDE NUCLEIC ACIDS RNGTT, CGAS, SARNP FFAR3 3460/4885TDP1 78/4885EYA2 1080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.