Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933917 | 0.98 | PDK2 (0.44) | PDK2AHRMAPK1MAPTFTO | |
| SCHEMBL23285076 | 0.92 | PDK2 (0.51) | PDK2AHRMAPK1MAPTFTO | |
| SCHEMBL29603442 | 0.92 | PDK2 (0.51) | PDK2AHRMAPK1MAPTFTO | |
| SCHEMBL17816867 | 0.90 | MAPK1 (0.44) | PDK2AHRMAPK1MAPTCYP2C19 | |
| SCHEMBL31753805 | 0.89 | MAPK1 (0.45) | PDK2AHRMAPK1MAPTCYP2C19 | |
| SCHEMBL22891353 | 0.89 | MAPK1 (0.45) | PDK2AHRMAPK1MAPTCYP2C19 | |
| SCHEMBL23285069 | 0.89 | PDK2 (0.47) | PDK2AHRMAPK1DRD2DRD4 | |
| SCHEMBL23372663 | 0.87 | ELANE (0.40) | PDK2AHRMAPK1MAPTFTO | |
| SCHEMBL24027778 | 0.87 | PDK2 (0.40) | PDK2AHRMAPK1MAPTFTO | |
| SCHEMBL23372347 | 0.86 | PDK2 (0.46) | PDK2AHRMAPK1MAPTFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-10573818-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, EFNA1 | PDK2 893/4885AHR 3751/4885MAPK1 355/4885 |
| US-10573818-B2 | Materials for organic electroluminescent devices | PIEZO1, LEF1, EFNA1 | PDK2 893/4885AHR 3751/4885MAPK1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.