Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.74 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | CDC25A | P30304 | 2/20 | 0.58 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | FGF2 | P09038 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholestan-3-One SCHEMBL31415973 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL14078297 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL3034745 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL17817346 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL14313461 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL24151938 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL14360529 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL12273856 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL643015 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| Cholestan-3-One SCHEMBL30428888 | 1.00 | GPBAR1 (0.74) | GPBAR1SRD5A1SRD5A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252290-A2 | COMPOSITIONS AND METHODS FOR TREATING NOVEL CORONAVIRUS SARS-COV-2-MEDIATED INFLAMMATORY CONDITIONS | GRI BIO, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | GPBAR1 757/4885SRD5A1 2502/4885SRD5A2 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.